Goals by Harry Kane, Christian Eriksen and Korean star Son Heung-min inside the opening half hour saw Spurs beat the Welsh side 3-0, leapfrog Manchester City into second spot and go six points behind leaders Liverpool.
Pochettino, who despite garnering credit for developing young players is yet to win a trophy in his managerial career, says he will be able to fill the large gap that will be left with Son leaving for Asian Cup duty.
It was Kane's 14th league goal, moving him alongside Arsenal striker Pierre-Emerick Aubameyang atop the scoring list and one above current Golden Boot holder Mohamed Salah, the Liverpool forward. In-form Son was the next to find the net in the 26th minute, finishing well from a tight angle - the 11th goal Son has been involved in his last eight league starts.
"Us and Everton, we were the two teams who suffered the most difficult fixtures in this period [with four games in 10 days] and of course we congratulate the players because the effort was fantastic - and all the staff because they work so hard to provide all the best tools for the players to perform in the best way". "The league should enforce they play at Wembley now for the rest of the season".
"But I will be in a neutral position trying to enjoy the game". "I think we started the game well, we were so clinical from the beginning".
Cardiff City is in danger of relegation, now 16th out of 20 teams in the Premier League.
"All the planning goes out of the window", Cardiff manager Neil Warnock said. I was pleased we didn't just fold in the second half'.
Neil Warnock will therefore be disappointed and maybe a little concerned by what has happened in his side's past two home matches against Manchester United and Spurs.