The third day of protests takes place on Saturday, Dec 1, with widespread violence erupting, particularly in Paris around the Arc de Triomphe and several upscale neighbourhoods.
By mid-morning, 343 people had been detained in Paris, according to a Paris police spokeswoman.
"It's a catastrophe for business", Le Maire said on Sunday as he toured Paris streets affected by the protests which hit the country for the fourth consecutive weekend.
Protesters "don't want to keep Macron any more".
Police and protesters also clashed in the southern French cities of Marseille and Toulouse.
Macron has already offered protesters a string of concessions, including scrapping further rises in fuel taxes - a major climbdown for a president who had vowed not to be swayed, like his predecessors, by mass protests.
Nearly 1,000 people, almost 100 of them minors and most without police records, were being held in custody after the Saturday protests in the French capital, Paris chief prosecutor Remy Heitz said.
The protests started a month ago in response to plans by President Macron to raise an environmental tax on diesel.
On Saturday, the Eiffel Tower and other monuments and museums closed their doors for security reasons, as did top department stores on what should have been a peak shopping day.
Prime Minister Edouard Philippe appealed for restraint.
"I say this to Donald Trump and the French president says it too: leave our nation be". Although the precise cost of the protests to the French economy can not yet be quantified, the French retail federation estimates retailers alone have lost around 1 billion euros (Dh4 billion) since the protests began.
"This chaos has to end", said Andre Juillard, a doctor, as he stood in line with other tired Parisians at a bakery near the Eiffel Tower, which reopened along with other monuments and museums after closing for security reasons on Saturday.
While the truth is obvious about the real nature of these protests, that hasn't stopped Russian bots from causing mass calamity while wearing yellow Klan-robe-like vests.
Protesters ripped off the plywood protecting the windows and threw flares and other projectiles as they were repeatedly repelled by tear gas and water cannon.
But the demonstrations are spreading as concerned French citizens share their issues with Macron's government on social media.
Since the unrest began in November, four people have been killed in protest-related accidents. French police frisked protesters at train stations around the country, confiscating everything from heavy metal petanque balls to tennis rackets - anything that could remotely be used as a weapon.
At least three people have died during the riots while 1,043 others have been injured, including 222 members of the security forces.