But France banged in four goals in their last 16 game against Argentina, and will be hoping their formidable attacking trio of Antoine Griezmann, Olivier Giroud and Kylian Mbappe can turn it on again at the Nizhny Novgorod stadium.
France and Uruguay go head to head in the first of two quarter-finals on Friday, with the victor set to go up against either Brazil or Belgium in the last four.
With a defence built around the central pairing of Jose Gimenez and the vastly experienced 32-year-old Diego Godin - they also play together at Atletico Madrid - Uruguay have won all four games in Russian Federation, conceding a solitary goal.
Uruguay extinguished Cristiano Ronaldo's Portugal on a thrilling night in Sochi to reach the quarter-finals, with Edinson Cavani scoring two brilliant goals.
Brazil are the only other team to have conceded just the solitary goal so far.
While Uruguay can not boast individuals on a par with Lionel Messi, whose team was thoroughly bested by France on Saturday, Uruguay will be a tougher test for Didier Deschamps' men compared to their South American counterparts.
"If you let France have space it will be very hard", Uruguay's coach Oscar Tabarez said after securing a place in the quarter-finals.
And they are marshalled by Godin, now 121 caps and counting.
Didier Deschamps, France's coach, has already indicated that he is expecting a different kind of game from "solid" Uruguay from the seven-goal thriller in Kazan.
Whoever - and however - decides the match is likely to have to get one over on a domestic teammate.
"In a World Cup you have the top-level players", said Mbappe, who plays for Paris Saint-Germain.
Even if Cavani is ruled out, Barcelona's sometimes infuriating frontman Luis Suarez will still be on hand to lead the line and with the outstanding Diego Godin, perhaps the best defender in the entire competition, marshaling their backline it was take a whole lot of French resistance to break down the Uruguayan rearguard.