The 2010 FIFA World Cup victor with Spain believes Unai Emery's PSG, who played the match of the season previous year against Barca will go through in the quarter finals by eliminating Real Madrid.
In the end though, of course, Isco was feted for his role in Madrid's Champions League and La Liga double last season and a new bumper deal was agreed with Madrid in September, tying him to the club until 2022.
An overhaul of the playing squad at the Bernabeu is expected in the summer with the LaLiga side struggling, now sat in fourth place in the league and 19 points behind Barcelona.
"It's a very hard game, I am a Real Madrid ambassador and obviously I want them to win, but on the other hand, I like PSG and my great friend Neymar is there, and everyone loves him".
"In reality, you need a good mix of youngsters and veterans".
Or, maybe they were just publishing nonsense, because just a few hours later, reports from Germany surfaced with quotes from the man himself about the Real Madrid links.
He continued: "They have not bought big and thought that with the young players they can compensate for that". They have much more experience than Paris Saint-Germain.
"These rumours do not interest me and I have nothing more to say".
"Well, I didn't plan for anything other than being at Inter for five years, but then there was the possibility and I went because Madrid is a team where everyone wants to play". When we first won the Champions League again in 1998, we finished fourth in the league. "Everyone knows that Madrid has the DNA of victory and more in this competition". He added, "They should think about what they have and this year it's hard for Madrid, they have to keep going and end well".