He also said Israel views "with utmost gravity" Iranian attempts to gain a foothold in Syria or to provide advanced weapons to Hezbollah, its Lebanese proxy.
Saturday's so-called retaliatory strikes targeted Syrian positions north of Golan Heights where rockets were allegedly fired from on Israeli territories.
Israel has mostly stayed on the sidelines throughout Syria's civil war, now in its seventh year, responding only with limited strikes when fire has spilled into Israel.
Arab media reported at least two Syrian soldiers were killed in the strikes.
Later in the day, a source on the ground told RIA Novosti that the Israeli Air Forces struck the Syrian government forces when the troops have been repelling a massive attack of the al-Nusra Front terrorists.
The action was a response to what the IDF said were more than 10 projectiles fired into Israel from inside Syria.
The Israel Defense Forces (IDF) released a video on Twitter showing airstrikes on a Syrian army heavy machine gun position and two tanks.
"In a statement, the army says the strikes hit a two artillery positions and an ammunition truck belonging to the Syrian regime".
Israel Prime Minister Benjamin Netanyahu earlier this week denied Israel provides support to Syrian rebels after the Wall Street Journal reported a special Israeli unit was providing aid to rebels.
"We will respond strongly to any firing at our territory", he warned.
According to the IDF, one of the Syrian projectiles was itself intercepted by an Israeli Arrow-2 missile, prompting Israel to disclose that its planes were operating in foreign airspace.